SLENDER IDS Integrated Delivery System

The concept of combining a guide wire with a balloon catheter is not new; fixed-wire balloons were used in the nascent stages of PCI, and their utility was recognized and valued.  Technological limitations, however, limited their growth and continued use.

SLENDER IDS is the first advance in coronary stent delivery in more than 20 years, representing a new, more efficient approach to PCI.

By mounting a DES on a wire to create an ‘all-in-one‘ system, catheters are downsized, patient comfort is enhanced, procedures are streamlined and resource consumption is reduced.

From its soft, flexible distal tip incorporating ASAHI wire tip technology to its reinforced distal shaft enhancing pushability, SLENDER IDS incorporates years of improvement in guide wire, balloon, stent and drug coating technologies to create a new paradigm in coronary stenting.

ASAHI, recognized the world over as the leader in steerable guide wire technology, designs and manufactures the SLENDER IDS wire tip.  Engineered specifically for SLENDER IDS, ASAHI wire tip technology enables movement just as you imagine it.

 

Composite Core Design

ACT ONE, a critical component of Asahi Composite Core Design and ingenious enhancement to the 10 micron core wire, represents the latest Asahi wire technology against which all other wires are measured.

• Long core wire taper enhances trackability
• ACT ONE overwrap optimizes tip control and shape retention
• 1.2 gram tip load^* provides an optimal blend of flexibility and support

 

 

Legendary ASAHI Performance

Precise torque transmission and enhanced tactile feedback reduce whip to navigate frontline as well as tortuous vessels and sharp angulations.

With ASAHI wire tip technology redefining the boundaries of guide wire performance, SLENDER IDS provides deliverability like no other DES.

Hybrid Stent Design

A unique hybrid stent design with variable length struts cut from specially sourced fine grain cobalt chromium allows uniquely tight crimping to achieve profiles as low as HALF the crimped area of conventional stents^* without compromise to strut thickness, radial strength or recoil.

 

 

Proprietary Balloon Technology

Low-compliant balloon material  provides a whole new approach to safe and efficient stent delivery.

Specialized delivery balloon technology minimizes unwanted vessel contact during direct stenting.  A proprietary balloon pleating and puffing process creates balloon proximal and distal areas slightly larger in profile than the crimped stent to create a smooth leading edge during stent delivery,

• Enhancing crossability through tight stenoses
• Augmenting stent retention
• Limiting stent-to-vessel contact and adding drug coating protection

Ensuring optimal stent expansion is critical when direct stenting.  Svelte’s delivery balloon is designed for high pressure inflation(s) to achieve complete stent apposition.  This reduces the need for additional non-compliant post-dilatation balloons and potential for geographic miss.

 

DISCREET Drug Coating

DISCREET, a new class of drug coating utilizing an amino acid (PEA) carrier from DSM, a global leader in biomedical materials science and regenerative medicine, provides high mechanical integrity and promotes healing.  Designed for direct senting, it resists damage which may be encountered when crossing calcified and tortuous anatomy, ensuring complete and consistent drug elution to the target lesion.

Once delivered to the target lesion, 213 µg/cm² of sirolimus is eluted to the vessel wall over 60 days, with full bioresporption of the drug carrier occurring within 12 months.

Ensuring optimal stent expansion is critical when direct stenting.  Svelte’s delivery balloon is designed for high pressure inflation(s) to achieve complete stent apposition.  This reduces the need for additional non-compliant post-dilatation balloons and potential for geographic miss.

Safe and Durable Outcomes

The Svelte DES technologies deliver outstanding clinical results with low reintervention rates and consistent neointimal suppression across patient subsets as seen in the DIRECT II study.

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The ultra-low profile and reinforced proximal shaft of SLENDER IDS facilitates TRI and direct stenting, even in complex anatomy.  Despite 50% of investigators in the DIRECT I and II studies being first-time users of the IDS:

• 98% of cases were free from device failure
• 96% of lesions were direct stented successfully
• 74% of patients were treated via transradial approach

 

Extract Steps, Time and Cost from Procedures

Svelte technologies optimize the use of preciously scarce resources – time and people.

SLENDER IDS eliminates procedural steps, improving procedural efficiency. Ancillary products typically associated with conventional stenting procedures (guide wires, PTCA balloons and even guiding catheters) are eliminated or reduced, resulting in actual, real-time savings without changing physician practice, even in complex anatomy.

 

Reductions in procedure time by an average of 30% and $119 – $592 in material cost savings per case^1-3 were observed in clinical studies using SLENDER IDS.

And as the only DES indicated for use with diagnostic and smaller catheters (0.047″ ID), SLENDER IDS offers the opportunity to downsize catheters, reducing risk of bleeding complications and enhancing patient comfort.

The clinical benefits of transradial intervention (TRI) and direct stenting are well known.  So too are their ability to streamline procedures and provide cost containment.

Compared with conventional (femoral) stenting, the transradial approach offers the ability to positively impact patients, physicians and health care providers.  Stenting via transradial approach is associated with REDUCED:

• All-cause mortality⁴
• Bleeding complications^4,5
• Vascular complications^4,5
• Time to ambulation⁶
• Length of hospital stay⁶
• Reduced procedure costs⁷

For patients, reduced procedural discomfort, bleeding complications, time to ambulation and hospital stays greatly improve the coronary stenting experience.  The transradial approach is overwhelmingly preferred by patients undergoing both radial and femoral access: of 7,021 patients included in the RIVAL study evaluating the effects of radial versus femoral artery access, 90% preferred use of the radial artery as the access site for their next procedure⁸.

For physicians and health care providers living under increasingly onerous time and budget constraints where emphasis is increasingly placed on extracting costs from procedures while limiting readmissions, TRI can be a meaningful aid in reducing procedure time and cost without compromising long-term outcomes.

As the world’s lowest profile DES, SLENDER IDS downsizes the catheters necessary to complete basic or complex coronary artery stenting.  Lower catheter size facilitates TRI, enhancing patient comfort and reducing risk of bleeding complications.